Pharmacopsychiatry. 2013 Jan;46(1):37-8. doi: 10.1055/s-0032-1316383. Epub 2012 Jul 20.
This paper reports the case of a 65-year-old depressed man without somatic illnesses in whom monotherapy with i. v. citalopram induced delirium. He was admitted to a closed geriatric ward as a psychotically depressed patient with somatic and depressive delusions, and suicidal thoughts. Because he rejected all oral medications, monotherapy was initiated with 20 mg of i. v. citalopram per day. After 3 days, he became delirious and physically aggressive. This description of acute hyperkinetic delirium associated with i. v. citalopram therapy is the first one of this kind addressing side effects of i. v. citalopram.
这篇论文报告了一例 65 岁抑郁男性患者的病例,该患者在单独使用静脉注射西酞普兰治疗后出现了谵妄。他因躯体和抑郁妄想以及自杀念头而被收入封闭的老年病房,作为精神病性抑郁患者。由于他拒绝服用所有口服药物,因此开始每天单独使用 20 毫克静脉注射西酞普兰进行治疗。3 天后,他出现了谵妄和身体攻击行为。这种与静脉注射西酞普兰治疗相关的急性高动力性谵妄的描述是首例针对静脉注射西酞普兰的副作用的报告。