d'Arminio Monforte A, Novati R, Galli M, Marchisio P, Massironi E, Tornaghi R, Saracco A, Principi N, Moroni M
Clinic of Infectious Diseases, University of Milan, Italy.
AIDS. 1990 Nov;4(11):1141-4. doi: 10.1097/00002030-199011000-00014.
T-lymphocyte subsets and serum immunoglobulins were assayed in 27 neonates and 12 infants younger than 6 months, all born to HIV-seropositive mothers. No differences in T-lymphocyte subsets between the 27 seropositive and 34 seronegative infants were found at birth. Twelve seroreverted and 14 infected children were followed. CD4+ cell counts were significantly lower in the latter at 3 and 24 months of age. Serum immunoglobulin levels and CD8+ percentages became higher in the infected group, starting from the sixth month, while CD4+ percentages and CD4+/CD8+ ratios became lower, starting from the twelfth month.
对27名新生儿和12名6个月以下婴儿进行了T淋巴细胞亚群和血清免疫球蛋白检测，这些婴儿均为HIV血清阳性母亲所生。出生时，27名血清阳性婴儿和34名血清阴性婴儿的T淋巴细胞亚群没有差异。对12名血清转阴儿童和14名感染儿童进行了随访。在3个月和24个月大时，后者的CD4 +细胞计数显著较低。从第六个月开始，感染组的血清免疫球蛋白水平和CD8 +百分比升高，而从第十二个月开始，CD4 +百分比和CD4 + / CD8 +比值降低。
