Conte-Devolx B, Legros J J, Poirier R, Giraud P, Gillioz P, Oliver C
Poumon Coeur. 1979;35(4):201-4.
Plasma AVP level, neurophysins and osmolality have been measured in 10 patients with oat cell carcinoma of the lung but without any biological signs of syndrome of inappropriate secretion of ADH (SIADH), before and 15 mn after an intravenous injection of Ethanol. No statistically significant difference was noted in the AVP, neurophysins and osmolality values between 10 patients with asymptomatic oat cell carcinoma and control population (10 normal volunteers, 12 patients with non neoplasic lung pathology and 10 patients with different lung carcinoma). We concluded that AVP and neurophysins cannot be considered as a good tumoral marker in the detection of oat cell carcinoma of the lung.
对10例肺燕麦细胞癌患者在静脉注射乙醇前及注射后15分钟测定了血浆抗利尿激素(AVP)水平、神经垂体素和渗透压,这些患者无抗利尿激素分泌不当综合征(SIADH)的任何生物学体征。10例无症状肺燕麦细胞癌患者与对照组人群(10名正常志愿者、12例非肿瘤性肺部疾病患者和10例不同类型肺癌患者)之间,AVP、神经垂体素和渗透压值无统计学显著差异。我们得出结论,在肺燕麦细胞癌的检测中,AVP和神经垂体素不能被视为良好的肿瘤标志物。