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[俄罗斯西北部长寿人群的端粒长度]

[Telomere length in the population of long-lived persons of North-West region of Russia].

作者信息

Smirnova T Iu, Runov A L, Vonskiĭ M S, Spivak D L, Zakharchuk A G, Mikhel'son V M, Spivak I M

出版信息

Tsitologiia. 2012;54(5):439-45.

PMID:22827042
Abstract

Interdisciplinary study of telomere length, polymorphism of genes of renin-angiotensin (ACE) and serotonin (5HTR2A and 5HTTPR) systems in population of aged and old inhabitants of the North-West of Russia was conducted, in their relations to data from clinical and geriatric anamnesis, and psychological functioning. Regular link between telomere length and respondent's age was demonstrated in subgroups of old respondents and long-livers, by method of factor analysis.

摘要

对俄罗斯西北部老年和高龄居民群体的端粒长度、肾素 - 血管紧张素(ACE)和血清素(5HTR2A 和 5HTTPR)系统基因多态性进行了跨学科研究,研究它们与临床和老年病史数据以及心理功能之间的关系。通过因子分析方法,在老年受访者和长寿者亚组中证明了端粒长度与受访者年龄之间的规律联系。

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