Kheng Cheah P, Rahman Nik H
Department of Emergency Medicine, School of Medical Sciences, USM, Kota Bharu, 16150, Malaysia.
Int J Emerg Med. 2012 Jul 24;5(1):31. doi: 10.1186/1865-1380-5-31.
The aim of this study was to determine the usefulness of end tidal carbon dioxide (ETCO2) monitoring in hypotensive shock patients presenting to the ED.
This was a prospective observational study in a tertiary ED. One hundred three adults in shock with hypotension presenting to the ED were recruited into the study. They were grouped according to different types of shock, hypovolemic, cardiogenic, septic and others. Vital signs and ETCO2 were measured on presentation and at 30-min intervals up to 120 min. Blood gases and serum lactate levels were obtained on arrival. All patients were managed according to standard protocols and treatment regimes. Patient survival up to hospital admission and at 30 days was recorded.
Mean ETCO2 for all patients on arrival was 29.07 ± 9.96 mmHg. Average ETCO2 for patients in hypovolemic, cardiogenic and septic shock was 29.64 ± 11.49, 28.60 ± 9.87 and 27.81 ± 7.39 mmHg, respectively. ETCO2 on arrival was positively correlated with systolic and diastolic BP, MAP, bicarbonate, base excess and lactate when analyzed in all shock patients. Early ETCO2 measurements were found to be significantly lower in patients who did not survive to hospital admission (p = 0.005). All patients who had ETCO2 ≤ 12mmHg died in the ED. However, normal ETCO2 does not ensure patient survival.
The use of ETCO2 in the ED has great potential to be used as a method of non-invasive monitoring of patients in shock.
本研究的目的是确定呼气末二氧化碳(ETCO2)监测在急诊科就诊的低血压休克患者中的作用。
这是一项在三级急诊科进行的前瞻性观察性研究。103名因低血压休克而到急诊科就诊的成年人被纳入研究。他们根据休克的不同类型进行分组,即低血容量性、心源性、感染性和其他类型。在就诊时及之后每隔30分钟测量一次生命体征和ETCO2,直至120分钟。到达时采集血气和血清乳酸水平。所有患者均按照标准方案和治疗方案进行处理。记录患者直至入院时及30天时的存活情况。
所有患者到达时的平均ETCO2为29.07±9.96 mmHg。低血容量性、心源性和感染性休克患者的平均ETCO2分别为29.64±11.49、28.60±9.87和27.81±7.39 mmHg。在所有休克患者中进行分析时,到达时的ETCO2与收缩压、舒张压、平均动脉压、碳酸氢盐、碱剩余和乳酸呈正相关。发现未存活至入院的患者早期ETCO2测量值显著较低(p = 0.005)。所有ETCO2≤12mmHg的患者均在急诊科死亡。然而,ETCO2正常并不能确保患者存活。
在急诊科使用ETCO2有很大潜力作为一种对休克患者进行无创监测的方法。