Cui H L, Ma L, Zhu R Q
China-Japan Friendship Hospital.
Zhonghua Nei Ke Za Zhi. 1990 Jul;29(7):422-4, 445.
Nine patients with SLE were treated with plasmapheresis (PP); eight of them having active disease improved rapidly and significantly both in clinical and laboratory parameters. The longest remission period was up to 17 months. The common side effects were hypocalcemia and urticaria but they did not necessitate cessation of therapy. The following treatment course is suggested: PP two to three times a week for two weeks with an exchange amount of 1.5 liters of plasma each time. In order to prevent the patients from antibody rebound phenomenon, administration of steroids and immunosuppressive agents following PP treatment is necessary.
9例系统性红斑狼疮患者接受了血浆置换治疗；其中8例患有活动性疾病的患者在临床和实验室指标方面均迅速且显著改善。最长缓解期达17个月。常见的副作用是低钙血症和荨麻疹，但这些副作用并不需要停止治疗。建议采用以下治疗方案：每周进行2至3次血浆置换，持续两周，每次置换血浆量为1.5升。为防止患者出现抗体反弹现象，在血浆置换治疗后给予类固醇和免疫抑制剂是必要的。
