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Genetic susceptibility to therapy-related leukemia after Hodgkin lymphoma or non-Hodgkin lymphoma: role of drug metabolism, apoptosis and DNA repair.

作者信息

Ding Y, Sun C-L, Li L, Li M, Francisco L, Sabado M, Hahn B, Gyorffy J, Noe J, Larson G P, Forman S J, Bhatia R, Bhatia S

出版信息

Blood Cancer J. 2012 Mar;2(3):e58. doi: 10.1038/bcj.2012.4. Epub 2012 Mar 2.

DOI:10.1038/bcj.2012.4
PMID:22829253
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3317523/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fef4/3317523/184a21b4aaf7/bcj20124f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fef4/3317523/184a21b4aaf7/bcj20124f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fef4/3317523/184a21b4aaf7/bcj20124f1.jpg

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本文引用的文献

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Altered hematopoietic cell gene expression precedes development of therapy-related myelodysplasia/acute myeloid leukemia and identifies patients at risk.造血细胞基因表达改变先于治疗相关骨髓增生异常/急性髓系白血病的发生，并可识别出有风险的患者。
Cancer Cell. 2011 Nov 15;20(5):591-605. doi: 10.1016/j.ccr.2011.09.011.
2
Ancestry informative marker sets for determining continental origin and admixture proportions in common populations in America.用于确定美洲普通人群大陆起源和混合比例的祖先信息标记集。
Hum Mutat. 2009 Jan;30(1):69-78. doi: 10.1002/humu.20822.
3
Genetic susceptibility to cancer: the role of polymorphisms in candidate genes.
白血病前期克隆性造血与治疗相关髓系肿瘤的风险：一项病例对照研究。
Lancet Oncol. 2017 Jan;18(1):100-111. doi: 10.1016/S1470-2045(16)30626-X. Epub 2016 Dec 3.
4
Genetic variation as a modifier of association between therapeutic exposure and subsequent malignant neoplasms in cancer survivors.基因变异作为癌症幸存者治疗暴露与后续恶性肿瘤之间关联的修饰因素。
Cancer. 2015 Mar 1;121(5):648-63. doi: 10.1002/cncr.29096. Epub 2014 Oct 29.
5
Caspase-9 is required for normal hematopoietic development and protection from alkylator-induced DNA damage in mice.半胱天冬酶-9对于小鼠正常造血发育以及免受烷化剂诱导的DNA损伤具有必要性。
Blood. 2014 Dec 18;124(26):3887-95. doi: 10.1182/blood-2014-06-582551. Epub 2014 Oct 27.
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Therapy-related myelodysplasia and acute myeloid leukemia.治疗相关性骨髓增生异常综合征和急性髓系白血病。
Semin Oncol. 2013 Dec;40(6):666-75. doi: 10.1053/j.seminoncol.2013.09.013.
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Clin Cancer Res. 2000 Oct;6(10):4091-5.
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Inference of population structure using multilocus genotype data.利用多位点基因型数据推断群体结构。
Genetics. 2000 Jun;155(2):945-59. doi: 10.1093/genetics/155.2.945.