早期宫颈癌的保留生育功能手术。
Fertility-sparing surgery for early-stage cervical cancer.
作者信息
Ribeiro Cubal Adelaide Fernanda, Ferreira Carvalho Joana Isabel, Costa Maria Fernanda Martins, Branco Ana Paula Tavares
机构信息
Obstetrics and Gynecology Service, Gynecology Department, Centro Hospitalar Tâmega e Sousa, E.P.E., 4564-007 Penafiel, Portugal.
出版信息
Int J Surg Oncol. 2012;2012:936534. doi: 10.1155/2012/936534. Epub 2012 Jul 8.
Abstract
Nowadays cervical cancer is diagnosed in many women who still want to have children. This led to the need to provide fertility-sparing treatments. The main goal is to maintain reproductive ability without decreasing overall and recurrence-free survival. In this article, we review data on procedures for fertility preservation, namely, vaginal and abdominal trachelectomy, less invasive surgery and neoadjuvant chemotherapy. For each one, oncological and obstetrical outcomes are analyzed. Comparing to traditionally offered radical hysterectomy, the overall oncologic safety is good, with promising obstetrical outcomes.
摘要
如今，许多仍希望生育的女性被诊断出患有宫颈癌。这就导致了需要提供保留生育功能的治疗方法。主要目标是维持生殖能力，同时不降低总体生存率和无复发生存率。在本文中，我们回顾了关于生育力保存程序的数据，即阴道和腹式宫颈切除术、微创手术和新辅助化疗。对每一种方法，我们都分析了肿瘤学和产科结局。与传统的根治性子宫切除术相比，总体肿瘤学安全性良好，产科结局也很有前景。
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