Rema P, Ahmed Iqbal
Division of Surgical Oncology, Regional Cancer Centre, Trivandrum, Kerala India.
J Obstet Gynaecol India. 2014 Aug;64(4):234-8. doi: 10.1007/s13224-014-0572-x. Epub 2014 Jun 3.
Fertility preservation is one of the major concerns of young patients diagnosed with gynecological cancer. With newer treatment regimens and better surgical techniques, survival rates after cancer treatment have improved, hence preservation of fertility has recently become an important issue in the treatment of gynecological cancers. Fertility sparing surgery may be an option for early-stage cervical cancer with the development of loop excision techniques and radical trachelectomy which allows a radical approach to cervix cancer at the same time preserving the uterus and thus fertility. Fertility preservation is possible in Stage 1 epithelial ovarian cancers, germ cell ovarian tumors, and borderline cancers. Hormonal therapy with progestin agents is effective in early endometrial cancer. In patients desiring future pregnancy, fertility sparing options must be explored before starting treatment for gynecologic cancers.
生育力保存是被诊断为妇科癌症的年轻患者主要关注的问题之一。随着更新的治疗方案和更好的手术技术,癌症治疗后的生存率有所提高,因此生育力保存最近已成为妇科癌症治疗中的一个重要问题。随着环形切除技术和根治性宫颈切除术的发展,保留生育功能的手术可能是早期宫颈癌的一种选择,这种手术在根治宫颈癌的同时能够保留子宫,从而保留生育能力。对于Ⅰ期上皮性卵巢癌、卵巢生殖细胞肿瘤和交界性肿瘤,生育力保存是可行的。孕激素类药物的激素治疗对早期子宫内膜癌有效。对于希望未来怀孕的患者,在开始妇科癌症治疗前必须探索保留生育功能的选择。