Vázquez Alonso Fernando, Berrio Campos Raquel, Puche Sanz Ignacio, Segura Sánchez Manuel, Molina Hernandez Jose Miguel, Flores Martin Jose Francisco, Cózar Olmo Jose Manuel
Servicio de Urología, Hospital Universitario Virgen de las Nieves, Avenida de las Fuerzas Armadas, No. 2, 18014 Granada, Spain.
Case Rep Urol. 2012;2012:940269. doi: 10.1155/2012/940269. Epub 2012 Jul 8.
Keratinizing squamous metaplasia of the bladder is rare and is usually associated with urinary tract infections and chronic irritation. It is considered a precancerous condition of squamous cell carcinoma, especially when more than 50% of the bladder surface is affected. Medical treatment cannot eradicate this lesion. When it is limited to a small area of the bladder, transurethral resection is possible. Annual cystoscopy with multiple biopsies as well as annual upper tract imaging is proposed in the follow up of these patients. We present a preliminary 2-year followup report of a keratinizing squamous metaplasia of the bladder in a 28-year-old female patient with no previous risk factors.
膀胱角化性鳞状化生较为罕见，通常与尿路感染和慢性刺激有关。它被认为是鳞状细胞癌的一种癌前病变，尤其是当膀胱表面受累超过50%时。医学治疗无法根除这种病变。当病变局限于膀胱的小区域时，可进行经尿道切除术。建议对这些患者进行随访时每年进行膀胱镜检查并多次活检，以及每年进行上尿路影像学检查。我们报告了一名28岁无既往危险因素的女性患者膀胱角化性鳞状化生的初步2年随访报告。
