Seĭbil' V B, Malyshkina L P
Zh Mikrobiol Epidemiol Immunobiol. 2012 May-Jun(3):107-13.
Problem of poliomyelitis eradication is examined in the review. After the eradication of wild poliovirus, vaccine poliomyelitis virus continues to circulate in the human population. In rare cases it can cause the development of the disease. The authors describe disadvantages of the use of oral and inactivated poliomyelitis vaccines and note that by using oral poliomyelitis vaccine and eradication only of wild poliovirus, eradication of poliomyelitis as an infection will not succeed. As one of the approaches to reach this goal the authors propose the use of various enterovirus interference. Use of live enterovirus vaccine is described and its advantages and disadvantages are examined.
该综述探讨了根除脊髓灰质炎的问题。野生脊髓灰质炎病毒根除后，疫苗衍生脊髓灰质炎病毒仍在人群中传播。在罕见情况下，它可导致疾病的发生。作者描述了口服和灭活脊髓灰质炎疫苗使用的缺点，并指出仅使用口服脊髓灰质炎疫苗以及仅根除野生脊髓灰质炎病毒，无法成功根除作为一种感染性疾病的脊髓灰质炎。作为实现这一目标的方法之一，作者提议利用各种肠道病毒干扰。文中描述了活肠道病毒疫苗的使用情况，并对其优缺点进行了探讨。
