Kondrashova T V, Luchnik N V
Genetika. 1990 Oct;26(10):1783-90.
Formation of single-stranded DNA regions was investigated during the presynthetic stage of human lymphocyte cell cycle. Two peaks of single-stranded region production were found in about the middle and near the end of the G1 stage. Both the peaks appeared some hours earlier in gamma-irradiated cells than in control. Experiments showed that the periods of the peak formation coincided with the terms when time-effect dependence for gamma-induced chromosomal aberrations changed its character. The interpretation of the results supposes existence of inherent for the G1 stage process of genetic material correction.
在人类淋巴细胞细胞周期的合成前期，对单链DNA区域的形成进行了研究。在G1期大约中间位置和接近末期发现了两个单链区域产生的峰值。在受γ射线照射的细胞中，这两个峰值出现的时间比对照组早几个小时。实验表明，峰值形成的时期与γ射线诱导的染色体畸变的时间效应依赖性改变其特征的时期一致。对结果的解释假定G1期存在遗传物质校正的固有过程。
