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秘鲁利马早产儿视网膜病变致盲的社会负担。

The societal burden of blindness secondary to retinopathy of prematurity in Lima, Peru.

机构信息

Emory University, Department of Ophthalmology, Atlanta, Georgia, USA.

出版信息

Am J Ophthalmol. 2012 Oct;154(4):750-5. doi: 10.1016/j.ajo.2012.04.003. Epub 2012 Jul 24.

Abstract

PURPOSE

To determine the cost-effectiveness of laser treatment for retinopathy of prematurity (ROP) in Lima, Peru.

DESIGN

A cost-of-illness study (in US dollars) to determine the direct cost of treatment, the indirect lifetime cost of blindness, and the quality-adjusted life years.

METHODS

The direct cost of ROP-related treatment was determined by reviewing data retrospectively from a social security sector hospital. The indirect cost was determined using national economic data of Peru published by the Central Information Agency (CIA), including the per capita gross domestic product, the sex-adjusted income distribution, and years spent in the work force. Indirect costs per child that were avoided by treatment were calculated using the known natural history of ROP vs evidence-based treatment.

RESULTS

For ROP-related neonatal blindness in Peru, we estimate the total indirect cost saving at $197,753 per child and the direct cost of laser treatment at $2496 per child. The societal lifetime cost saving per child is estimated at $195,257. The mean annual income per educated adult in Peru is $8000 and treating 1 child is equivalent to employing 24 educated Peruvians per year. The generational cost savings for society is approximately $516 million, or the equivalent of 64,500 educated Peruvian work years.

CONCLUSIONS

The societal burden of blindness far exceeds the costs of treatment per child. Proper screening and treatment of ROP prevents blindness and leads to substantial cost savings for society. Public health policy in Peru and other middle-income countries should consider financial impact when allocating healthcare resources.

摘要

目的

确定秘鲁利马早产儿视网膜病变(ROP)激光治疗的成本效益。

设计

一项疾病成本研究(以美元计算),以确定治疗的直接成本、失明的终身间接成本和调整后的生命质量。

方法

通过回顾社会保障部门医院的回溯数据,确定 ROP 相关治疗的直接成本。间接成本是利用秘鲁中央情报局(CIA)公布的国家经济数据确定的,包括人均国内生产总值、性别调整后的收入分布以及劳动力年限。通过 ROP 的已知自然史与循证治疗,计算出避免治疗的每个儿童的间接成本。

结果

对于秘鲁 ROP 相关新生儿失明,我们估计每个儿童的总间接成本节省为 197753 美元,激光治疗的直接成本为 2496 美元。每个儿童的社会终身成本节省估计为 195257 美元。秘鲁受过教育的成年人的平均年收入为 8000 美元,治疗 1 名儿童相当于每年雇用 24 名秘鲁受教育者。社会的代际成本节省约为 5.16 亿美元,相当于 64500 名受过教育的秘鲁工作年。

结论

失明给社会带来的负担远远超过每个儿童的治疗成本。ROP 的适当筛查和治疗可以预防失明,并为社会带来巨大的成本节省。秘鲁和其他中等收入国家的公共卫生政策在分配医疗资源时应考虑财务影响。

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