Rheumatology Division, Roger Williams Medical Center, Boston University, Boston, MA, USA.
J Clin Rheumatol. 2012 Aug;18(5):253-6. doi: 10.1097/RHU.0b013e318262e3f9.
Henoch-Schönlein purpura (HSP) is considered a benign disease of children. We report a severe case of HSP in an adult causing renal failure and gastrointestinal (GI) hemorrhage. Despite aggressive treatment with corticosteroids, cyclophosphamide, and plasmapheresis, the patient developed massive GI bleeding from 2 Dieulafoy lesions and died weeks after bowel resection. Although uncommon, when massive GI hemorrhage occurs, actively bleeding Dieulafoy lesions, although uncommon, should be suspected and evaluated early.
过敏性紫癜（HSP）被认为是儿童的良性疾病。我们报告了一例成人严重 HSP 病例，导致肾功能衰竭和胃肠道（GI）出血。尽管使用皮质类固醇、环磷酰胺和血浆置换进行了积极治疗，但患者仍因 2 处Dieulafoy 病变发生大量胃肠道出血，并在肠切除数周后死亡。尽管不常见，但当发生大量胃肠道出血时，应怀疑并早期评估是否存在活动性出血的 Dieulafoy 病变。
