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听力损失与获得性免疫缺陷综合征:系统评价

Hearing loss and acquired immune deficiency syndrome: systematic review.

作者信息

Araújo Eliene da Silva, Zucki Fernanda, Corteletti Lilian Cássia Bórnia Jacob, Lopes Andrea Cintra, Feniman Mariza Ribeiro, Alvarenga Kátia de Freitas

机构信息

Department of Speech-Language Pathology and Audiology, Bauru School of Dentistry, Universidade de São Paulo, Bauru, SP, Brazil.

出版信息

J Soc Bras Fonoaudiol. 2012;24(2):188-92. doi: 10.1590/s2179-64912012000200017.

Abstract

PURPOSE

To investigate the occurrence of hearing loss in individuals with HIV/AIDS and their characterization regarding type and degree.

RESEARCH STRATEGY

It was conducted a systematic review of the literature found on the electronic databases PubMed, EMBASE, ADOLEC, IBECS, Web of Science, Scopus, Lilacs and SciELO.

SELECTION CRITERIA

The search strategy was directed by a specific question: "Is hearing loss part of the framework of HIV/AIDS manifestations?", and the selection criteria of the studies involved coherence with the proposed theme, evidence levels 1, 2 or 3, and language (Portuguese, English and Spanish).

DATA ANALYSIS

We found 698 studies. After an analysis of the title and abstract, 91 were selected for full reading. Out of these, 38 met the proposed criteria and were included on the review.

RESULTS

The studies reported presence of conductive, sensorineural, and mixed hearing loss, of variable degrees and audiometric configurations, in addition to tinnitus and vestibular disorders. The etiology can be attributed to opportunistic infections, ototoxic drugs or to the action of virus itself. The auditory evoked potentials have been used as markers of neurological alterations, even in patients with normal hearing.

CONCLUSION

HIV/AIDS patients may present hearing loss. Thus, programs for prevention and treatment of AIDS must involve actions aimed at auditory health.

摘要

目的

调查感染人类免疫缺陷病毒/获得性免疫缺陷综合征(HIV/AIDS)的个体中听力损失的发生情况及其类型和程度特征。

研究策略

对在电子数据库PubMed、EMBASE、ADOLEC、IBECS、科学网、Scopus、Lilacs和SciELO上检索到的文献进行系统综述。

选择标准

检索策略由一个特定问题引导:“听力损失是否属于HIV/AIDS表现范畴?”,研究的选择标准包括与主题的一致性、证据水平为1、2或3以及语言(葡萄牙语、英语和西班牙语)。

数据分析

我们共找到698项研究。在对标题和摘要进行分析后,挑选出91项进行全文阅读。其中,38项符合拟定标准并被纳入综述。

结果

研究报告了除耳鸣和前庭障碍外,还存在不同程度和听力图配置的传导性、感音神经性及混合性听力损失。病因可归因于机会性感染、耳毒性药物或病毒本身的作用。即使听力正常的患者,听觉诱发电位也已被用作神经学改变的标志物。

结论

HIV/AIDS患者可能出现听力损失。因此,艾滋病预防和治疗项目必须包含针对听力健康的行动。

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