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从麦冬中分离得到的两种新化合物。

Two new compounds isolated from Liriope muscari.

机构信息

National Institutes for Food and Drug Control, Beijing 100050, China.

出版信息

Molecules. 2012 Jul 25;17(8):8773-81. doi: 10.3390/molecules17088773.

Abstract

Two new compounds, (2S,3R)-methyl 7-hydroxy-2-(4-hydroxy-3-methoxy-phenyl)-3-(hydroxymethyl)-2,3-dihydrobenzofuran-5-carboxylate (1) and (4R,5S)-5-(3-hydroxy-2,6-dimethylphenyl)-4-isopropyldihydrofuran-2-one (2), tentatively named norcurlignan and limlactone, respectively, were isolated from Liriope muscari, together with the known compound (-)-pinoresinol (3). The structures of these compounds were elucidated and characterized on the basis of 1D NMR, 2D NMR, CD and MS data. The in vitro antioxidant activities of compounds 1-3 were assessed by the DPPH and ABTS scavenging methods.

摘要

从石蒜中分离得到了两个新化合物,(2S,3R)-甲基 7-羟基-2-(4-羟基-3-甲氧基苯基)-3-(羟甲基)-2,3-二氢苯并呋喃-5-羧酸酯(1)和(4R,5S)-5-(3-羟基-2,6-二甲基苯基)-4-异戊基二氢呋喃-2-酮(2),分别暂定名为 norcurlignan 和 limlactone,同时还分离得到了已知化合物(-)-松脂醇(3)。基于 1D NMR、2D NMR、CD 和 MS 数据,解析并鉴定了这些化合物的结构。采用 DPPH 和 ABTS 清除法评估了化合物 1-3 的体外抗氧化活性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b14d/6268434/40ece77cbb3f/molecules-17-08773-g001.jpg

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