Geisler Todd M
BioMatRx, LLC, 5775 Wayzata Boulevard, Suite 700, Minneapolis, MN 55416, USA.
Dent Clin North Am. 2012 Jul;56(3):603-26. doi: 10.1016/j.cden.2012.05.010.
The management of a tooth with incomplete root maturation and a necrotic pulp is an endodontic and a restorative challenge. Apexification procedures alone leave the tooth in a weakened state and at risk for reinfection. Regenerative endodontic procedures potentially offer advantages, including the possibility of hard tissue deposition and continued root development. Case studies have reported regeneration of human pulplike tissues in vivo, but there is no protocol that reliably regenerates pulplike tissue. This article summarizes historical, current, and future regenerative treatment approaches.
对牙根发育不全且牙髓坏死的牙齿进行治疗是牙髓病学和修复学面临的一项挑战。单纯的根尖诱导成形术会使牙齿处于脆弱状态，且有再次感染的风险。牙髓再生治疗可能具有优势，包括硬组织沉积和牙根持续发育的可能性。病例研究报告了在体内人类牙髓样组织的再生，但尚无可靠地使牙髓样组织再生的方案。本文总结了过去、当前和未来的再生治疗方法。
