• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

治疗选择:再生性牙髓治疗程序的生物学基础

Treatment options: biological basis of regenerative endodontic procedures.

作者信息

Hargreaves Kenneth M, Diogenes Anibal, Teixeira Fabricio B

机构信息

Department of Endodontics, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.

出版信息

Pediatr Dent. 2013 Mar-Apr;35(2):129-40.

PMID:23635981
Abstract

Dental trauma occurs frequently in children and often can lead to pulpal necrosis. The occurrence of pulpal necrosis in the permanent but immature tooth represents a challenging clinical situation because the thin and often short roots increase the risk of subsequent fracture. Current approaches for treating the traumatized immature tooth with pulpal necrosis do not reliably achieve the desired clinical outcomes, consisting of healing of apical periodontitis, promotion of continued root development, and restoration of the functional competence of pulpal tissue. An optimal approach for treating the immature permanent tooth with a necrotic pulp would be to regenerate functional pulpal tissue. This review summarizes the current literature supporting a biological rationale for considering regenerative endodontic treatment procedures in treating the immature permanent tooth with pulp necrosis.

摘要

牙外伤在儿童中经常发生,且常常会导致牙髓坏死。恒牙但牙根未发育完全时发生牙髓坏死是一种具有挑战性的临床情况,因为牙根薄且通常较短会增加后续牙根折断的风险。目前治疗牙髓坏死的未发育成熟恒牙的方法不能可靠地实现预期的临床效果,这些效果包括根尖周炎的愈合、促进牙根的持续发育以及恢复牙髓组织的功能能力。治疗牙髓坏死的未发育成熟恒牙的最佳方法是使功能性牙髓组织再生。本综述总结了当前的文献,这些文献支持在治疗牙髓坏死的未发育成熟恒牙时考虑采用再生性牙髓治疗程序的生物学原理。

相似文献

1
Treatment options: biological basis of regenerative endodontic procedures.治疗选择:再生性牙髓治疗程序的生物学基础
Pediatr Dent. 2013 Mar-Apr;35(2):129-40.
2
Treatment options: biological basis of regenerative endodontic procedures.治疗方案:再生牙髓治疗的生物学基础。
J Endod. 2013 Mar;39(3 Suppl):S30-43. doi: 10.1016/j.joen.2012.11.025.
3
Treatment of a large cystlike inflammatory periapical lesion associated with mature necrotic teeth using regenerative endodontic therapy.使用再生性牙髓治疗术治疗与成熟坏死牙相关的大型囊肿样根尖周炎性病变。
J Endod. 2014 Dec;40(12):2081-6. doi: 10.1016/j.joen.2014.07.027. Epub 2014 Oct 5.
4
Responses of immature permanent teeth with infected necrotic pulp tissue and apical periodontitis/abscess to revascularization procedures.感染性坏死牙髓组织和根尖周炎/脓肿的未成熟恒牙对血管再生活性治疗的反应。
Int Endod J. 2012 Mar;45(3):294-305. doi: 10.1111/j.1365-2591.2011.01978.x. Epub 2011 Nov 14.
5
Recommendations for using regenerative endodontic procedures in permanent immature traumatized teeth.关于在恒牙未成熟受创牙中应用牙髓再生术的建议。
Dent Traumatol. 2012 Feb;28(1):33-41. doi: 10.1111/j.1600-9657.2011.01044.x. Epub 2011 Jul 27.
6
Considerations for regeneration procedures.再生程序的注意事项。
Pediatr Dent. 2013 Mar-Apr;35(2):141-52.
7
Is pulp regeneration necessary for root maturation?牙髓再生对于牙根成熟是否必要?
J Endod. 2013 Oct;39(10):1291-5. doi: 10.1016/j.joen.2013.06.019. Epub 2013 Aug 27.
8
Regenerative treatment of an immature, traumatized tooth with apical periodontitis: report of a case.未成熟、外伤后伴根尖周炎牙齿的再生治疗:病例报告
J Endod. 2008 May;34(5):611-6. doi: 10.1016/j.joen.2008.02.029.
9
Clinical considerations for regenerative endodontic procedures.再生性牙髓治疗程序的临床考量
Dent Clin North Am. 2012 Jul;56(3):603-26. doi: 10.1016/j.cden.2012.05.010.
10
Case series: management of immature permanent teeth with pulpal necrosis: a case series.病例系列:牙髓坏死的未成熟恒牙的治疗:病例系列
Pediatr Dent. 2013 Jan-Feb;35(1):55-60.

引用本文的文献

1
Root development of immature necrotic permanent teeth following regenerative endodontic process: Case series.再生牙髓治疗后未成熟坏死恒牙的牙根发育:病例系列
Dent Res J (Isfahan). 2025 Jul 24;22:28. doi: 10.4103/drj.drj_1_25. eCollection 2025.
2
The Effects of Azithromycin Modified Triple Antibiotic Paste in Resolving Periapical Inflammation.阿奇霉素改良三联抗生素糊剂对根尖周炎的治疗效果
Int Dent J. 2025 Jul 15;75(5):100895. doi: 10.1016/j.identj.2025.100895.
3
Regenerative Endodontic Therapies: Harnessing Stem Cells, Scaffolds, and Growth Factors.
再生牙髓治疗:利用干细胞、支架和生长因子。
Polymers (Basel). 2025 May 26;17(11):1475. doi: 10.3390/polym17111475.
4
Microbial Loads in Traumatized Immature Teeth and Their Impact on the Treatment Outcomes of Regenerative Endodontic Treatment: A Randomized Clinical Trial Comparing Chlorhexidine and Calcium Hydroxide.外伤年轻恒牙的微生物负荷及其对牙髓再生治疗效果的影响:一项比较氯己定和氢氧化钙的随机临床试验
Dent Traumatol. 2025 Oct;41(5):501-515. doi: 10.1111/edt.13062. Epub 2025 Mar 27.
5
Clinical and radiographic evaluation of two different apexification protocols in traumatized immature permanent incisors.两种不同根尖诱导成形术方案用于外伤后未成熟恒切牙的临床及影像学评估
Ulus Travma Acil Cerrahi Derg. 2025 Jan;31(1):23-31. doi: 10.14744/tjtes.2024.31532.
6
The effect of fibroblast growth factor-2 on the outcomes of tooth replantation: A systematic review of animal studies.成纤维细胞生长因子-2 对牙再植预后影响的系统评价:动物研究的系统评价。
Sci Prog. 2024 Jan-Mar;107(1):368504241228964. doi: 10.1177/00368504241228964.
7
A Potential Intracanal Medicament, 2-Hydroxyisocaproic Acid (HICA): Cytotoxicity, Genotoxicity, and Its Effect on SCAP Differentiation.一种潜在的根管内药物,2-羟基异己酸(HICA):细胞毒性、遗传毒性及其对根尖乳头干细胞分化的影响。
Dent J (Basel). 2023 Nov 27;11(12):270. doi: 10.3390/dj11120270.
8
Analyzes In Silico Indicate the lncRNAs MIR31HG and LINC00939 as Possible Epigenetic Inhibitors of the Osteogenic Differentiation in PDLCs.分析表明,lncRNAs MIR31HG 和 LINC00939 可能是 PDLCs 成骨分化的表观遗传抑制剂。
Genes (Basel). 2023 Aug 18;14(8):1649. doi: 10.3390/genes14081649.
9
The efficacy of concentrated growth factor and platelet-rich fibrin as scaffolds in regenerative endodontic treatment applied to immature permanent teeth: a retrospective study.浓缩生长因子和富血小板纤维蛋白作为支架在再生性牙髓治疗应用于未成熟恒牙中的疗效:一项回顾性研究。
BMC Oral Health. 2023 Jul 14;23(1):482. doi: 10.1186/s12903-023-03164-y.
10
Biomimetic Approaches in Clinical Endodontics.临床牙髓病学中的仿生方法。
Biomimetics (Basel). 2022 Dec 6;7(4):229. doi: 10.3390/biomimetics7040229.