Hall C L, Higgs C M, Notarianni L
University of Bath Postgraduate School of Medicine, Royal United Hospital, UK.
J Hum Hypertens. 1990 Oct;4(5):501-7.
To identify the prevalence and magnitude of clinic changes in blood pressure and determine their effects on the diagnosis and treatment of hypertension, 268 patients with a BP greater than or equal to 160/95 mmHg on three consecutive occasions (twice in the general practitioner's surgery and once in the hospital clinic) recorded a home BP series with an electronic sphygmomanometer. Of these patients, 114 had never received antihypertensive treatment and 154 were receiving treatment. On return to the hospital clinic (second clinic visit) the BP was measured independently by the patient and doctor using electronic and mercury sphygmomanometers respectively and compared with the mean BP of the home series. In some 80% of both untreated and treated patients the second clinic BP was higher than the mean BP of the home series and in some 40% of patients a clinic rise of greater than 20/10 mmHg was recorded. Clinic falls in BP occurred in some 20% of both untreated and treated patients, but averaged only 4/4 mmHg. Treatment decisions based on a mean diastolic blood pressure of greater than or equal to 95 mmHg in the home series resulted in antihypertensive treatment not being started in 38% of untreated patients and not increased in 31% or reduced in 16% of treated patients when treatment would have been started, increased or continued unchanged on the basis of the second clinic (fourth recorded) diastolic blood pressure of greater than or equal to 95 mmHg. A patient recorded home series provides a representative sample of BP which distinguishes patients with sustained hypertension from those with clinic hypertension and may help reduce the overdiagnosis and overtreatment of mild hypertension.
为了确定血压临床变化的患病率和幅度,并确定其对高血压诊断和治疗的影响,268例连续三次血压大于或等于160/95 mmHg的患者(两次在全科医生诊所,一次在医院门诊)使用电子血压计记录家庭血压系列。在这些患者中,114例从未接受过抗高血压治疗,154例正在接受治疗。回到医院门诊(第二次门诊就诊)时,患者和医生分别使用电子和水银血压计独立测量血压,并与家庭血压系列的平均血压进行比较。在大约80%的未治疗和治疗患者中,第二次门诊血压高于家庭血压系列的平均血压,并且在大约40%的患者中记录到门诊血压升高超过20/10 mmHg。在大约20%的未治疗和治疗患者中出现门诊血压下降,但平均仅为4/4 mmHg。基于家庭血压系列中平均舒张压大于或等于95 mmHg做出的治疗决定,导致38%的未治疗患者未开始抗高血压治疗,31%的治疗患者未增加治疗,16%的治疗患者减少治疗;而根据第二次门诊(第四次记录)舒张压大于或等于95 mmHg本应开始、增加或维持不变治疗。患者记录的家庭血压系列提供了一个具有代表性的血压样本,可区分持续性高血压患者和临床高血压患者,并可能有助于减少轻度高血压的过度诊断和过度治疗。