Mikuni K, Ishikawa Y, Takahashi S, Hirosawa H, Ichihashi H
Department of Pediatrics, School of Medicine, Kyorin University.
Jpn J Antibiot. 1990 Aug;43(8):1462-7.
We studied the clinical efficacy of cefdinir (CFDN), a new oral cephalosporin, in 18 children with ages 2 years and 4 months to 11 years and 4 months with pediatric infections. The diagnoses consisted of respiratory tract infections in 15 cases, impetigo in 2 and balanoposthitis in 1. Clinical efficacies were excellent in 11 patients and good in 7, with an efficacy rate of 100%. Bacteriologically, 9 (64.3%) of the 14 strains of clinical isolates were eradicated. No side effects nor abnormal laboratory findings were observed. We have concluded that CFDN is a useful antibiotic for the treatment of mild to moderate pediatric infections.
我们研究了新型口服头孢菌素头孢地尼（CFDN）对18名年龄在2岁4个月至11岁4个月的患有小儿感染的儿童的临床疗效。诊断结果包括15例呼吸道感染、2例脓疱病和1例龟头炎。11例患者临床疗效优异，7例良好，有效率为100%。从细菌学角度看，14株临床分离菌株中有9株（64.3%）被根除。未观察到副作用及实验室检查异常。我们得出结论，CFDN是治疗轻至中度小儿感染的一种有用的抗生素。
