Gr.T.Popa University of Medicine and Pharmacy Iasi, Pulmonary Disease University Hospital, Pulmonary Disease Department, 30 Dr I Cihac Str, 700115 Iasi, Romania.
Expert Opin Investig Drugs. 2012 Nov;21(11):1607-18. doi: 10.1517/13543784.2012.712112. Epub 2012 Jul 27.
This is the annual perspective paper on the discontinued drugs in the field of pulmonary allergy, gastrointestinal, and arthritis conditions. It is part of series of papers discussing drugs discontinued from clinical development in the previous year and presented according to therapeutic indication. Specifically, this paper presents the 23 compounds developed for various inflammatory conditions and 10 pulmonary drugs which were discontinued in 2011. Information for this perspective was derived from a search of the Pharmaprojects database for drugs discontinued after reaching Phase-I - III clinical trials.
这是一篇关于肺部过敏、胃肠道和关节炎领域已停产药物的年度观点论文。它是一系列讨论上一年度临床开发中停产药物的论文之一,按照治疗适应症进行了分类。具体来说,本文介绍了为各种炎症性疾病开发的 23 种化合物和 2011 年停产的 10 种肺部药物。本观点的信息来源于对 Pharmaprojects 数据库中在完成 I 期-III 期临床试验后停产的药物进行的搜索。