Kanra G, Gürsavaş M, Aydin M, Cengizlier R, Seçmeer G, Ceyhan M
Hacettepe Universitesi, Pediatri Anabilim Dali.
Mikrobiyol Bul. 1990 Jul;24(3):226-36.
Ceftazidime, a beta-lactamase resistant cephalosporin, was administered intravenously to 33 patients with various infections. The age range was between 3 days and 15 years and substantial underlying disease was present in 90% of the patients and 72% had malignancy. Seventeen (51.5%) were in critical condition and twenty had granulocytopenia. Clinical and microbiological results were evaluated and overall clinical response was 88%. No major adverse effects were encountered. Ceftazidime was an effective and safe therapy for serious infections and neutropenic patients.
头孢他啶是一种耐β-内酰胺酶的头孢菌素，对33例患有各种感染的患者进行了静脉给药。年龄范围在3天至15岁之间，90%的患者存在严重基础疾病，72%患有恶性肿瘤。17例（51.5%）病情危急，20例有粒细胞减少症。对临床和微生物学结果进行了评估，总体临床有效率为88%。未出现重大不良反应。头孢他啶对严重感染和中性粒细胞减少患者是一种有效且安全的治疗方法。
