Commonwealth Orthopaedics and Rehabilitation, 3620 Joseph Siewick Drive, Fairfax, VA 22033, U.S.A.
Arthroscopy. 2012 Aug;28(8):1079-86. doi: 10.1016/j.arthro.2012.05.010.
To compare the results and outcome of anterior cruciate ligament (ACL) reconstruction using autogenous hamstring tendon versus fresh-frozen allograft anterior tibialis tendon.
A prospective randomized study was conducted from September 2002 to October 2006. We randomized 147 patients to undergo ACL reconstruction with either autogenous hamstring or fresh-frozen allograft anterior tibialis tendon. Of these patients, 102 (69%) completed a minimum of 2 years' follow-up. There were 54 patients in the hamstring group (73% of those originally enrolled in the group) and 48 patients in the allograft group (66%). All patients underwent standardized subjective and objective evaluation with functional outcome assessments (International Knee Documentation Committee [IKDC]), and standardized radiographs were also obtained.
The mean age was 32.0 years for the autograft group and 33.3 years for the allograft group. There was no difference in stability between the 2 groups (P > .05). The mean IKDC subjective score was 91.0 for the autograft group and 90.9 for the allograft group (P > .05). The functional IKDC scores for the autograft group were normal in 46 patients (85%), nearly normal in 7 patients (13%), and severely abnormal in 1 patient. For the allograft group, the functional IKDC scores were normal in 43 patients (90%) and nearly normal in 5 (10%) (P > .05). There were 4 reoperations in the allograft group and 3 reoperations in the autograft group. No patient underwent revision ACL surgery or planned to undergo revision surgery because of instability in either group during the study period despite the 1 patient in the autograft group with a pivot shift and a maximum manual KT measurement (MEDmetric, San Diego, CA) of 5 mm.
The use of fresh-frozen anterior tibialis allograft (non-treated) for ACL reconstruction produced similar subjective and functional outcomes at 24 months' minimal follow-up compared with patients undergoing ACL reconstruction with autograft hamstring tendon.
Level II, prospective comparative study.
比较自体腘绳肌腱与新鲜冷冻同种异体胫骨前肌腱重建前交叉韧带（ACL）的结果。
一项前瞻性随机研究于 2002 年 9 月至 2006 年 10 月进行。我们将 147 例患者随机分为自体腘绳肌腱或新鲜冷冻同种异体胫骨前肌腱 ACL 重建组。其中 102 例（69%）完成了至少 2 年的随访。在腘绳肌腱组中有 54 例患者（该组最初入组患者的 73%），同种异体组中有 48 例患者（66%）。所有患者均进行了标准化的主观和客观评估，包括功能结果评估（国际膝关节文献委员会[IKDC]），并获得了标准化的 X 线片。
自体移植物组的平均年龄为 32.0 岁，同种异体组为 33.3 岁。两组间稳定性无差异（P＞.05）。自体移植物组的 IKDC 主观评分平均为 91.0，同种异体组为 90.9（P＞.05）。自体移植物组的功能 IKDC 评分正常 46 例（85%），接近正常 7 例（13%），严重异常 1 例。同种异体组中，功能 IKDC 评分正常 43 例（90%），接近正常 5 例（10%）（P＞.05）。同种异体组中有 4 例患者需要再次手术，自体移植物组中有 3 例患者需要再次手术。尽管自体移植物组中有 1 例患者出现前抽屉试验阳性和最大手动 KT 测量值（MEDmetric，圣地亚哥，CA）为 5mm，但在研究期间，两组均无患者因不稳定而进行 ACL 翻修手术或计划进行翻修手术。
与自体腘绳肌腱 ACL 重建相比，使用新鲜冷冻同种异体胫骨前肌腱（未经处理）进行 ACL 重建在 24 个月的最低随访时可产生相似的主观和功能结果。
Ⅱ级，前瞻性比较研究。
