Caillot E, Denis F
Service de radiothérapie, CHU de Poitiers, France.
Cancer Radiother. 2012 Sep;16(5-6):358-63. doi: 10.1016/j.canrad.2012.05.005. Epub 2012 Jul 28.
Mucositis is a major side effect induced by radiotherapy and/or chemotherapy of head and neck cancer. This toxicity impacts patient's quality of life and may compromise optimal treatments. Pathophysiology, risk factors, incidence and consequences of mucositis will be discussed in this review. Its management remains principally supportive (pain medication and nutritional support); however, in recent years several studies have revealed that the use of low level energy laser is particularly useful in the prevention and treatment of chemo- and radio-induced mucositis.
口腔黏膜炎是头颈部癌症放疗和/或化疗引起的主要副作用。这种毒性会影响患者的生活质量,并可能影响最佳治疗效果。本文将讨论口腔黏膜炎的病理生理学、危险因素、发病率和后果。其治疗主要仍为支持性治疗(止痛药物和营养支持);然而,近年来多项研究表明,低强度能量激光在预防和治疗化疗及放疗引起的口腔黏膜炎方面特别有用。