Scully Crispian, Epstein Joel, Sonis Stephen
World Health Organisation Collaborating Centre for Oral Health, Disability and Culture, University College London, University of London, London WC1X 8LD, United Kingdom.
Head Neck. 2004 Jan;26(1):77-84. doi: 10.1002/hed.10326.
Oral mucositis is a common sequel of radiotherapy, chemotherapy, and radiochemotherapy in patients with cancer or patients requiring hemopoietic stem cell transplants. Mucositis has a direct and significant impact on the duration of disease remission and cure rates, because it is a treatment-limiting toxicity. Mucositis also affects survival because of the risk of infection and has a significant impact on quality of life and cost of care.
This article reviews publications on the diagnosis and management of oral mucositis accessible from a MEDLINE search using as key words mucositis, radiotherapy, chemotherapy, hemopoietic stem cell transplant, and oral.
Conventional care of patients with mucositis is currently essentially palliative, with good oral hygiene, narcotic analgesics, and topical palliative mouth rinses.
口腔黏膜炎是癌症患者或需要造血干细胞移植的患者接受放疗、化疗及放化疗后的常见后遗症。黏膜炎对疾病缓解期和治愈率有直接且重大的影响，因为它是一种限制治疗的毒性反应。黏膜炎还因感染风险而影响生存率，并对生活质量和护理成本有重大影响。
本文回顾了通过医学文献数据库检索获取的关于口腔黏膜炎诊断和管理的出版物，检索关键词为黏膜炎、放疗、化疗、造血干细胞移植和口腔。
目前，对黏膜炎患者的常规护理本质上主要是姑息性的，包括保持良好的口腔卫生、使用麻醉性镇痛药以及局部姑息性漱口液。
