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[测定危重新生儿肾素、醛固酮和血管加压素水平的临床价值]

[Clinical value of determining the levels of renin, aldosterone and vasopressin in newborn infants in critical conditions].

作者信息

Antonov A G, Baĭbarina E N, Volobuev A I, Kiseleva Z M, Tsybul'skaia I S, Burkova A S, Evteeva N V

出版信息

Pediatriia. 1990(10):8-12.

PMID:2284186
Abstract

The concentrations of aldosterone, vasopressin and plasma renin activity were measured in cord blood and on days 1, 3 and 5 of life in 71 newborn infants from the risk group at the development of critical conditions. Vasopressin was discovered to play a substantial role in the development of critical conditions. The lack of a considerable vasopressin ejection in response to a delivery trouble and the growth of its concentration by day 5 of life are prognostically unfavourable. Hyperactivity of the renin-aldosterone system determines the newborns' proneness to liquid and sodium retention.

摘要

对71名处于危急状况发生风险组的新生儿,测定了其脐血以及出生后第1、3和5天的醛固酮、血管加压素浓度和血浆肾素活性。发现血管加压素在危急状况的发生中起重要作用。对分娩困难缺乏显著的血管加压素释放,以及出生后第5天其浓度升高,在预后方面是不利的。肾素-醛固酮系统的活性过高决定了新生儿易于出现液体和钠潴留。

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