Swenson R R, Beckwith B E, Lamberty K J, Krebs S J, Tinius T P
Psychology Department, University of North Dakota, Grand Forks 58202.
Peptides. 1990 Sep-Oct;11(5):927-32. doi: 10.1016/0196-9781(90)90011-s.
Rats whose mothers had been treated with 1 microgram of arginine vasopressin (AVP) or oxytocin (OXT), 15 mg of caffeine, or saline on days 13-19 of gestation were given training on a passive avoidance response as adults. Female rats whose mothers had been exposed to either AVP or caffeine demonstrated enhanced retention of the response. No effects were found for male rats or for exposure to oxytocin. These results suggest that prenatal exposure to AVP or caffeine produced sexually dimorphic effects on learning and that the effects are specific to the structure of AVP.
在妊娠第13至19天，其母亲接受过1微克精氨酸加压素（AVP）或催产素（OXT）、15毫克咖啡因或生理盐水处理的大鼠，成年后接受了被动回避反应训练。其母亲接触过AVP或咖啡因的雌性大鼠表现出对该反应的记忆增强。未发现对雄性大鼠或接触催产素的大鼠有影响。这些结果表明，产前接触AVP或咖啡因对学习产生了性别差异效应，且这些效应是AVP结构特有的。
