氯诺昔康的临床药代动力学研究。
Clinical pharmacokinetic studies with lornoxicam.
作者信息
Turner P, Johnston A
机构信息
Department of Clinical Pharmacology, St. Bartholomew's Hospital, London, UK.
出版信息
Postgrad Med J. 1990;66 Suppl 4:S28-9.
PMID:2284218
Abstract
Pharmacokinetic data from several studies in young and elderly human subjects are reviewed. Lornoxicam appears to be extensively metabolized and no unchanged drug has been found in the urine. It has a relatively short elimination half-life (about 4 hours), and no significant differences in pharmacokinetic data have been found between young and elderly volunteers.
摘要
回顾了多项针对年轻和老年人体受试者的研究中的药代动力学数据。氯诺昔康似乎被广泛代谢，尿液中未发现原形药物。其消除半衰期相对较短（约4小时），年轻和老年志愿者之间的药代动力学数据未发现显著差异。
Zotero 插件