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原发性乳腺鳞状细胞癌:病例报告及治疗决策

Primary squamous cell carcinoma of the breast: case report and management decisions.

作者信息

Gupta Nidhi, Vashisht Rajesh, Nimbran Vinod, Gupta Rakesh, Dhingra Neerja, Bhutani Anjali

机构信息

Department of Radiation Oncology, Grecian Super Speciality Hospital, Sector 69, Mohali, Punjab, India.

出版信息

J Cancer Res Ther. 2012 Apr-Jun;8(2):323-5. doi: 10.4103/0973-1482.99006.

Abstract

Though breast carcinoma is one of the most common malignancies worldwide, adequate knowledge of this disease is still very poor. Pure primary squamous cell carcinoma of breast is one such mystery, which is encountered very rarely. Its clinical behavior should not be correlated with the standard infiltrating duct carcinoma of breast. It follows an atypical presentation in terms of tumor size, lymph node and systemic spread. It is generally a triple negative tumor with an aggressive behavior and resistance to standard chemotherapeutic regimens. Management decisions need to be individualized with emphasis toward platinum-based chemotherapy and targeted therapy.

摘要

尽管乳腺癌是全球最常见的恶性肿瘤之一,但对这种疾病的充分了解仍然非常匮乏。乳腺原发性纯鳞状细胞癌就是这样一种神秘的疾病,极为罕见。其临床行为不应与乳腺标准浸润性导管癌相关联。在肿瘤大小、淋巴结及全身扩散方面,它呈现出非典型表现。它通常是一种三阴性肿瘤,具有侵袭性且对标准化疗方案耐药。治疗决策需要个体化,重点是铂类化疗和靶向治疗。

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