Sepahdari Ali R, Mong Sandy
Department of Radiological Sciences, David Geffen School of Medicine, University of California Los Angeles, 757 Westwood Plaza, Suite 1621D, Los Angeles, CA, 90095, USA.
Surg Radiol Anat. 2013 Jan;35(1):19-24. doi: 10.1007/s00276-012-1001-4. Epub 2012 Jul 28.
Contrast-enhanced MRI is the mainstay for detecting pathology in the skull base foramina and nerve canals, through demonstration of abnormal enhancement. When MRI is contraindicated, or unable to differentiate tumor from non-neoplastic pathology, high-resolution skull base CT is indicated to assess for nerve canal or foramen widening, which is currently determined subjectively. The purpose of this study is to provide objective CT criteria that may help distinguish between normal asymmetry and pathologic nerve canal or foramen widening.
Temporal bone CTs of 50 consecutive adults without facial or trigeminal nerve pathology were retrospectively reviewed. Short axis measurements were obtained in the axial plane for three segments of the facial nerve canal (labyrinthine, tympanic, and mastoid), foramen ovale, pterygoid canal and foramen rotundum on both sides in each subject. Descriptive statistics were obtained, and left-right asymmetry was calculated.
Nerve canal/foramen size was normally distributed across subjects, with a minimal amount of left-right asymmetry. The upper limits of the 95 % confidence interval for absolute left-right asymmetry were: 0.25, 0.21, and 0.15 mm for the labyrinthine, tympanic, and mastoid segments of the facial nerve canal, respectively; 0.62 mm for foramen ovale; 0.36 mm for pterygoid canal; 0.38 mm for foramen rotundum.
Relative asymmetry is more important than absolute size for determining nerve canal/foramen abnormality. These normative data may be useful adjuncts to subjective assessments of nerve canal/foramen size when using skull base CT to identify tumor.
增强磁共振成像(MRI)是检测颅底孔道和神经管病变的主要手段,通过显示异常强化来实现。当MRI为禁忌或无法区分肿瘤与非肿瘤性病变时,需行高分辨率颅底CT以评估神经管或孔道是否增宽,目前这一评估是主观的。本研究的目的是提供客观的CT标准,以帮助区分正常不对称与病理性神经管或孔道增宽。
回顾性分析50例无面神经或三叉神经病变的连续成年患者的颞骨CT。在轴位平面上,对每位患者双侧的面神经管三段(迷路段、鼓室段和乳突段)、卵圆孔、翼管和圆孔进行短轴测量。获得描述性统计数据,并计算左右不对称性。
神经管/孔道大小在各受试者中呈正态分布,左右不对称程度最小。绝对左右不对称性的95%置信区间上限分别为:面神经管迷路段0.25mm、鼓室段0.21mm、乳突段0.15mm;卵圆孔0.62mm;翼管0.36mm;圆孔0.38mm。
对于确定神经管/孔道异常,相对不对称性比绝对大小更重要。在使用颅底CT识别肿瘤时,这些标准数据可能有助于对神经管/孔道大小进行主观评估。