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个性化针具改良用于CT引导下经圆孔对上颌神经进行经皮射频消融以治疗三叉神经第二支(V2)神经痛。

Personalized needle modification for CT-guided percutaneous infrazygomatic radiofrequency ablation of the maxillary nerve through the foramen rotundum in order to treat V2 trigeminal neuralgia.

作者信息

Huang Bing, Yao Ming, Liu Qianying, Chen Yajing, Ni Huadong, Li Zhang, Xie Keyue, Fei Yong, Li Langping

机构信息

Department of Anesthesiology and Pain Medical Center, First Affiliated Hospital of Jiaxing University, Jiaxing 314001, People's Republic of China.

Department of Anesthesiology, Ruijin Hospital Luwan Branch, Shanghai Jiao Tong University School of Medicine, Shanghai 200020, People's Republic of China.

出版信息

J Pain Res. 2019 Jul 26;12:2321-2329. doi: 10.2147/JPR.S207297. eCollection 2019.

Abstract

The computed tomography (CT)-guided radiofrequency ablation (RFA) of the maxillary nerve (V2) via foramen rotundum (FR) approach has been reported to offer the highest rates of pain relief in V2 trigeminal neuralgia (TN). However, the access to FR may be obstructed by the greater wing of the sphenoid bone. We report on an optimized CT-guided percutaneous infrazygomatic of maxillary nerve through the foramen rotundum (FR) to treat V2 trigeminal neuralgia (TN) using personalized RFA needles based on patient's individual CT-image parameters. 176 patients with isolated V2 TN were included. If the entry of the percutaneous needle into the FR canal was blocked by the greater wing of the sphenoid bone, straight RFA needles was bent at the tip with an angle α (the angle between the straight line from the external opening of FR to the skin entry point and the long axis of the FR canal). The maxillary nerve RFA was performed after confirmation with electrophysiological tests. Pain relief in the V2 territory and TN recurrence rate were followed for up to 60 months. Fifty-two patients (29.55%) required needle bending. The maxillary nerve thermal RFA resulted in analgesia in the V2 territory without affecting the V1 or V3 zone. TN recurrence rate at 6, 12, 24, 36, 48 and 60 months was 2.55%, 7.64%, 17.20%, 24.41%, 30.28% and 33.77%, respectively. The personalized needle modification technique for maxillary nerve RFA through FR is safe and effective to treat V2 TN.

摘要

据报道,经圆孔(FR)入路的计算机断层扫描(CT)引导下的上颌神经(V2)射频消融术(RFA)在V2三叉神经痛(TN)中提供了最高的疼痛缓解率。然而,圆孔的通路可能会被蝶骨大翼阻塞。我们报告了一种基于患者个体CT图像参数,通过圆孔(FR)对上颌神经进行优化的CT引导下经颧下入路,使用个性化RFA针治疗V2三叉神经痛(TN)。纳入了176例孤立性V2 TN患者。如果经皮穿刺针进入FR管的入口被蝶骨大翼阻塞,则将直的RFA针在尖端弯曲成角度α(从FR外口到皮肤穿刺点的直线与FR管长轴之间的角度)。在电生理测试确认后进行上颌神经RFA。随访V2区域的疼痛缓解情况和TN复发率长达60个月。52例患者(29.55%)需要弯曲穿刺针。上颌神经热RFA导致V2区域镇痛,而不影响V1或V3区域。6、12、24、36、48和60个月时TN的复发率分别为2.55%、7.64%、17.20%、24.41%、30.28%和33.77%。通过FR进行上颌神经RFA的个性化针改良技术治疗V2 TN是安全有效的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae1d/6666371/9ef61bb03033/JPR-12-2321-g0001.jpg

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