Glasgow & Clyde Weight Management Service, UK.
J Health Psychol. 2013 Apr;18(4):574-86. doi: 10.1177/1359105312451865. Epub 2012 Jul 27.
This study explored predictors of clinically meaningful improvement in health-related quality of life (HRQOL) among obese patients completing a specialist weight management programme. One hundred and ninety-nine adults aged from 20-88 with a BMI >30 with comorbidities or BMI>35 with/without comorbidities were sampled. The results suggested that both weight loss and changes in depression were significant predictors of HRQOL improvement. However, predictors differed between weight loss groups. Clinically meaningful improvement in HRQOL was found to be due to weight loss when participants had lost 5 kg or more in weight. In contrast, among individuals who lost 0.1-4.9 kg, improvement in HRQOL was accounted for by positive changes in depression scores.
本研究探讨了肥胖患者完成专业体重管理项目后健康相关生活质量（HRQOL）临床显著改善的预测因素。共抽样了 199 名年龄在 20-88 岁之间，BMI>30 且有合并症或 BMI>35 且有/无合并症的成年人。结果表明，体重减轻和抑郁变化均是 HRQOL 改善的显著预测因素。然而，预测因素在体重减轻组之间存在差异。当参与者体重减轻 5 公斤或更多时，发现 HRQOL 的临床显著改善归因于体重减轻。相比之下，在体重减轻 0.1-4.9 公斤的个体中，抑郁评分的积极变化解释了 HRQOL 的改善。
