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[差异化饮食疗法对慢性肝性脑病临床疗效及生化指标的影响]

[Effect of differentiated diet therapy on the clinical results and biochemical indicators in chronic hepatic encephalopathy].

作者信息

Szpakowicz T, Boroń P, Flisiak R, Bobrowska E, Kaczmarska A, Nowak H F, Zimnoch L

机构信息

Kliniki Chorób Zakaźnych Akademii Medycznej, Białymstoku.

出版信息

Przegl Lek. 1990;47(7):527-31.

PMID:2284419
Abstract

Effects of differentiated diet with reduced proteins or diet without proteins with simultaneous use of lactulose or the preparation enriched with aliphatic amino acids with aminosteril-hepa chain on the clinical results and the ammonia, phenols, alpha-amino nitrogen, tyrosine, phenylalanine and tryptophan++ concentrations in the serum have been studied. It has been demonstrated that limitations of proteins in the diet or diet without proteins with the use of lactulose or amino acids mixtures above does not influence significantly the clinical amelioration or biochemical indices of encephalopathy or coma during the liver cirrhosis course. Homogenates of the liver and brain of patients who died due to encephalopathy and liver cirrhosis showed high contents of ammonia, tyrosine, phenylalanine and tryptophan++.

摘要

研究了低蛋白分化饮食或无蛋白饮食同时使用乳果糖或富含脂肪族氨基酸与氨基甾体 - 肝链的制剂对临床结果以及血清中氨、酚类、α - 氨基氮、酪氨酸、苯丙氨酸和色氨酸++浓度的影响。结果表明,在肝硬化病程中,饮食中蛋白质的限制或无蛋白饮食同时使用上述乳果糖或氨基酸混合物,对脑病或昏迷的临床改善或生化指标没有显著影响。因脑病和肝硬化死亡患者的肝脏和脑组织匀浆显示氨、酪氨酸、苯丙氨酸和色氨酸++含量很高。

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