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克罗恩病并发小肠腺癌。

Adenocarcinoma of the small bowel in a patient with occlusive Crohn's disease.

机构信息

Lior Drukker, Yair Edden, Petachia Reissman, Department of General Surgery, Shaare Zedek Medical Center, Hebrew University, Hadassah School of Medicine, PO Box 3235, Jerusalem 91031, Israel.

出版信息

World J Gastrointest Oncol. 2012 Jul 15;4(7):184-6. doi: 10.4251/wjgo.v4.i7.184.

Abstract

A 40-year-old male, diagnosed with mild Crohn's disease (CD) 11 years ago but with no prior abdominal surgeries, was diagnosed with a small bowel stricture, due to ongoing abdominal pain and intolerance of enteral diet, and referred for surgical treatment. Exploratory laparoscopy revealed a white solid mass causing a near total jejunal obstruction with significant proximal dilatation. An adjacent small node was sampled for frozen biopsy, revealing a lymph node infiltrated with adenocarcinoma. Laparoscopic assisted small bowel resection and appendectomy were carried out. Final pathological results supported the initial report of diffuse small bowel adenocarcinoma. In conclusion, once a small bowel stricture associated with CD is suspected, rapid action should be considered to avoid late diagnosis of a neoplasia.

摘要

一位 40 岁男性,11 年前被诊断为轻度克罗恩病(CD),但无腹部手术史,因持续腹痛和不能耐受肠内饮食而被诊断为小肠狭窄,并转至外科治疗。腹腔镜探查显示一个白色实性肿块导致近完全性空肠梗阻,并伴有明显的近端扩张。一个相邻的小结节被取样进行冷冻活检,显示一个被腺癌浸润的淋巴结。进行了腹腔镜辅助小肠切除术和阑尾切除术。最终病理结果支持最初的弥漫性小肠腺癌报告。总之,一旦怀疑与 CD 相关的小肠狭窄,应迅速采取行动,避免对肿瘤的晚期诊断。

相似文献

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Adenocarcinoma of the small bowel in a patient with occlusive Crohn's disease.克罗恩病并发小肠腺癌。
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Small bowel adenocarcinoma presenting as a first manifestation of Crohn's disease: report of a case, and a literature review.
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Small bowel adenocarcinoma in Crohn's disease.克罗恩病中的小肠腺癌
Inflamm Bowel Dis. 2008 Aug;14(8):1154-7. doi: 10.1002/ibd.20393.
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The risk of cancer in patients with Crohn's disease.克罗恩病患者患癌风险
Dis Colon Rectum. 2007 Jun;50(6):839-55. doi: 10.1007/s10350-006-0848-z.

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