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克罗恩病中的小肠腺癌

Small bowel adenocarcinoma in Crohn's disease.

作者信息

Feldstein Richard C, Sood Shivani, Katz Seymour

机构信息

Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, North Shore University Hospital-Long Island Jewish Medical Center, New York University School of Medicine, Manhasset, New York, USA.

出版信息

Inflamm Bowel Dis. 2008 Aug;14(8):1154-7. doi: 10.1002/ibd.20393.

DOI:10.1002/ibd.20393
PMID:18275076
Abstract

Small bowel neoplastic disease is a rare but dreaded occurrence in Crohn's disease (CD) and the diagnosis is often disguised by nonspecific and varied presenting symptoms mimicking active or obstructive CD. As such, the diagnosis is all too often delayed, typically detected at a late stage, and with a poor prognosis. CD has become a well-recognized risk factor for the development of small bowel adenocarcinoma. The data, however, are limited and based on case reports, retrospective studies, and review of the literature.

摘要

小肠肿瘤性疾病在克罗恩病(CD)中虽罕见但令人恐惧,其诊断常被模仿活动性或梗阻性CD的非特异性和多样的症状所掩盖。因此,诊断常常延迟,通常在晚期才被发现,且预后不良。CD已成为公认的小肠腺癌发生的危险因素。然而,数据有限,基于病例报告、回顾性研究及文献综述。

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