Harada Sayaka, Tsuji Masahiro, Yoshida Takeshi
Department of Pediatrics, Kobe City Medical Center General Hospital, Kobe, Hyogo.
No To Hattatsu. 2012 Jul;44(4):315-9.
Treatment periods for bacterial meningitis are often very long, and often this prolonged treatment is based on the judgment of its effectiveness by the degree of enhancement on brain magnetic resonance imaging (MRI). In this study, we analyzed the contrast MRI in the acute and recovery phases of bacterial meningitis in twelve patients, and graded the contrast level of the subdural space and subarachnoid space separately. While the contrast level of the subarachnoid space increased with time in 4 cases, that of the subdural space increased in 10 cases, and 9 of them revealed a good prognosis without continuation of the treatment. These findings indicate that increased contrast level of the subdural space is common in the recovery phase of bacterial meningitis, and that repetitive MRI investigation is not valuable to determine the duration of treatment.
细菌性脑膜炎的治疗周期通常很长，而且这种延长治疗往往基于脑磁共振成像（MRI）增强程度对其疗效的判断。在本研究中，我们分析了12例细菌性脑膜炎患者急性期和恢复期的对比增强MRI，并分别对硬膜下间隙和蛛网膜下间隙的对比增强程度进行分级。蛛网膜下间隙的对比增强程度在4例患者中随时间增加，硬膜下间隙的对比增强程度在10例患者中增加，其中9例在未继续治疗的情况下预后良好。这些发现表明，硬膜下间隙对比增强程度增加在细菌性脑膜炎恢复期很常见，并且重复进行MRI检查对于确定治疗持续时间并无价值。
