Creutzig H, Schindler E, Reuter T D, Fröhlich D
Urologe A. 1979 Nov;18(6):316-20.
The catheter-free determination of the unilateral 131I-hippuran clearance correlates well with the unilateral clearance determination with 99mTc-DMSA in patients without obstruction. In patients with unilateral chronic obstruction the clearance of 131I-hippuran on the average is 13% higher than the clearance determined by the DMSA method. After successful correction of the obstruction the two values are identical. 123I-hippuran is foundin the renal pelvis already after 90 seconds in some cases of marked chronic obstruction. The functioning part of the involved kidney is therefore possibly overestimated whereas the DMSA uptake reflects the actual function. Both radioisotope methods should be applied preoperatively in order to evaluate the individual renal function. Functional scintigraphy in patients with obstruction should preferably be carried out with 123I-hippuran.
在无梗阻患者中,无导管测定单侧131I - 马尿酸清除率与用99mTc - DMSA测定单侧清除率相关性良好。在单侧慢性梗阻患者中,131I - 马尿酸的清除率平均比DMSA法测定的清除率高13%。梗阻成功解除后,这两个值相同。在一些明显慢性梗阻的病例中,90秒后肾盂中就可发现123I - 马尿酸。因此,受累肾脏的功能部分可能被高估,而DMSA摄取反映实际功能。两种放射性同位素方法都应在术前应用,以评估个体肾功能。对于梗阻患者,功能性闪烁显像最好使用123I - 马尿酸进行。