Department of Urology, Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Korea.
Int J Urol. 2012 Dec;19(12):1091-8. doi: 10.1111/j.1442-2042.2012.03106.x. Epub 2012 Jul 29.
To evaluate the clinical prognosis of incontinence and to determine the predictors for further recovery of urinary continence in patients not achieving urinary continence within 1 year after radical prostatectomy.
A total of 708 patients were evaluated regarding urinary continence status at 1 year after surgery from a prospectively maintained radical prostatectomy database. Of these, 73 (10.3%) did not recover urinary continence within 1 year after surgery. For these patients, incontinence status and the number of pads for urinary control were assessed serially.
In 708 patients, factors associated with the recovery of urinary continence within 1 year after radical prostatectomy were membranous urethral length, prostatic apex shape and patient age. Among 73 patients with urinary incontinence, 41 (56.2%) achieved urinary continence with a mean time of 15.4 months subsequent to the first year after radical prostatectomy (baseline). A younger age at surgery (P = 0.027) and one pad being required (vs ≥2 pads) at baseline (P = 0.046) were identified as independent factors for achievement of urinary continence within a further 2 years. Only the number of pads was a significant factor for further recovery of urinary continence in the longer follow up (hazard ratio 0.36, P = 0.029).
Compared with factors related to the prostate or membranous urethra, patient age and severity of incontinence at 1 year after radical prostatectomy are more strongly related to the recovery of urinary continence later than 1 year after surgery. These findings might help to decide whether a definite treatment is required for persistent incontinence beyond 1 year after radical prostatectomy.
评估尿失禁的临床预后,并确定在根治性前列腺切除术后 1 年内未达到尿控的患者进一步恢复尿控的预测因素。
从前瞻性维持的根治性前列腺切除术数据库中评估了 708 例患者术后 1 年的尿控状态。其中,73 例(10.3%)在术后 1 年内未恢复尿控。对这些患者进行了连续的尿失禁状态和控尿垫数量评估。
在 708 例患者中,与根治性前列腺切除术后 1 年内恢复尿控相关的因素包括膜部尿道长度、前列腺尖部形状和患者年龄。在 73 例尿失禁患者中,41 例(56.2%)在根治性前列腺切除术后 1 年后续发时达到尿控,平均时间为 15.4 个月(基线)。手术时年龄较小(P = 0.027)和基线时需要 1 个垫(vs ≥2 个垫)(P = 0.046)是在进一步 2 年内实现尿控的独立因素。只有垫的数量是在更长的随访时间内进一步恢复尿控的显著因素(风险比 0.36,P = 0.029)。
与与前列腺或膜部尿道相关的因素相比,患者年龄和根治性前列腺切除术后 1 年时的尿失禁严重程度与术后 1 年以后恢复尿控的关系更为密切。这些发现可能有助于决定在根治性前列腺切除术后 1 年以上持续尿失禁是否需要进行确定性治疗。