Department of Pharmacy, Faculty of Medicine, University of Tartu, Nooruse 1, 50411 Tartu, Estonia.
Int J Biol Macromol. 2012 Dec;51(5):939-45. doi: 10.1016/j.ijbiomac.2012.07.024. Epub 2012 Jul 27.
Solid-state and powder properties of softwood lignin and cellulose prepared by a new catalytic oxidation and acid precipitation method were characterized and compared with the commercial softwood and hardwood lignin and cellulose products. Catalytic pre-treated softwood lignin (CPSL) and cellulose (CPSC) were isolated from pine wood (Pinus sylvestris). CPSL with nearly micronized-scale particle size showed excellent powder flow and densification behavior due to the round shape and electrically minimum charged surface characteristics of particles. CPSL and the reference lignin studied were amorphous solids while CPSC exhibited a typical crystal lattice for cellulose I. In conclusion, physicochemical material properties of lignin and cellulose can be modified for biomedical and pharmaceutical applications with the present catalytic oxidation and acid precipitation method.
采用一种新的催化氧化和酸沉淀方法制备的软木木质素和纤维素的固态和粉末特性，并与商业软木和硬木木质素和纤维素产品进行了比较。催化预处理的软木木质素（CPSL）和纤维素（CPSC）是从松木（Pinus sylvestris）中分离出来的。由于颗粒的圆形形状和最小电荷表面特性，具有近微米级粒径的 CPSL 表现出优异的粉末流动性和致密化行为。CPSL 和研究的参考木质素为无定形固体，而 CPSC 则表现出纤维素 I 的典型晶格。总之，通过目前的催化氧化和酸沉淀方法，可以对木质素和纤维素的物理化学材料特性进行改性，以用于生物医学和制药应用。
