Pekhlivanov D, Rankov R, Pekhlivanov N, Lambev I, Minkova N
Vutr Boles. 1990;29(3):122-6.
The contemporary antiulcer treatment is performed with drugs which act unfavorably on the professional fitness on automobile and engine drivers. In 28 patients with newly discovered and untreated peptic ulcer disease the supporting treatment with Biotitin and Gastrozepin did not show unfavorable effect on the ability to concentrate, to fix the attention, fast choice of conduct and on the length of the latent period and the motion times. In comparison with 14 healthy persons the patients examined showed changes in their neurophysiological condition prior to the antiulcer treatment which correlate with the onset of the peptic ulcer disease, the disturbances of the prostaglandin synthesis and the development of functional beta-adrenergic protective reaction. The timely and modern antiulcer treatment is in the interest of safety of road traffic.
当代抗溃疡治疗所使用的药物对汽车和发动机驾驶员的职业健康有不利影响。在28例新发现且未经治疗的消化性溃疡病患者中，使用比奥替丁和胃长宁进行辅助治疗，对注意力集中能力、注意力固定、行为快速选择以及潜伏期和运动时间均未显示出不利影响。与14名健康人相比，接受检查的患者在抗溃疡治疗前神经生理状态发生了变化，这与消化性溃疡病的发作、前列腺素合成紊乱以及功能性β - 肾上腺素能保护反应的发展相关。及时且现代的抗溃疡治疗有利于道路交通安全。
