Stinghe R, Wipf R
Poumon Coeur. 1977;33(5):277-80.
A study of blood gasometry at rest and after exercise was carried out on 98 subjects: 49 healthy, 31 cases with "small airway disease" and 18 cases of clinically nondecompensated obstructive lung disease. The most interesting results arose from the study of PaO2. Its mean value increased after exercise in all groups, but in a manner less obvious as the bronchial obstruction appeared and increased. This increase was almost imperceptible in obstructive patients. The whole of gasometric behaviour ranged the subjects with "small airway disease" in an intermediate position between the normal controls and the obstructive patients. This finding leads the authors to suppose that the "small airway disease" implies the existence of disorders of intrapulmonary gas exchanges which foreshadow the obstructive disease.
对98名受试者进行了静息和运动后血气分析研究:49名健康人,31例“小气道疾病”患者,18例临床无失代偿的阻塞性肺病患者。最有趣的结果来自于对动脉血氧分压(PaO2)的研究。所有组运动后其平均值均升高,但随着支气管阻塞的出现和加重,升高的程度不那么明显。在阻塞性患者中,这种升高几乎难以察觉。整个血气分析行为将“小气道疾病”患者置于正常对照组和阻塞性患者之间的中间位置。这一发现使作者推测,“小气道疾病”意味着存在肺内气体交换紊乱,这是阻塞性疾病的先兆。