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评估茶在加拿大双重(3H/14C)性能测试计划中的基质作用。

Evaluation of tea as a matrix in a dual (3H/14C) performance testing program in Canada.

机构信息

National Calibration and Reference Centre, Radiation Protection Bureau, Health Canada, 775 Brookfield Road, P.L # 6302D, Ottawa, ON, Canada K1A 1C1.

出版信息

Health Phys. 2012 Sep;103(3):275-8. doi: 10.1097/HP.0b013e318258c7c8.

DOI:10.1097/HP.0b013e318258c7c8
PMID:22850232
Abstract

Urine is the most popular matrix used in performance testing programs (PTP) and inter-comparison programs (ICP) for bioassay. Because it comes from humans, there are concerns regarding its biosafety. For large programs, its collection can take several hours or days to complete. In addition, natural urine has an unpleasant smell, which tends to worsen with increasing storage time. In order to solve some of these problems, the Bioassay Section at the Radiation Protection Bureau in Health Canada has been investigating the use of tea in both PTP and ICP exercises. A method based on diluting tea steeps and scanning them in the UV-VIS range of the light spectrum to select appropriate concentrations as simulated urine for the programs has been published. So far, however, only single H and single C in tea have been studied. The results were found to be compatible and very successful under the S-106 standard of the Canadian Nuclear Safety Commission. This report is an extension of similar investigations and shows that tea samples spiked with both H and C (DUAL) are also compatible and produce excellent PTP results.

摘要

尿液是生物测定程序(PTP)和比对程序(ICP)中最常使用的基质,因为它来自人类,因此人们对其生物安全性存在担忧。对于大型程序而言,尿液采集可能需要数小时或数天才能完成。此外,天然尿液有异味,随着储存时间的延长,这种异味往往会恶化。为了解决其中的一些问题,加拿大卫生部辐射防护局的生物测定科一直在研究在 PTP 和 ICP 练习中使用茶。已经公布了一种基于稀释茶浸液并在光的光谱的 UV-VIS 范围内扫描它们以选择合适浓度作为程序模拟尿液的方法。然而,到目前为止,仅对茶中的单个 H 和单个 C 进行了研究。根据加拿大核安全委员会的 S-106 标准,发现这些结果是兼容的,并且非常成功。本报告是类似调查的扩展,表明同时添加 H 和 C(双掺)的茶样品也是兼容的,并能产生出色的 PTP 结果。

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