Division of General Internal Medicine, New York University School of Medicine, New York, NY, USA.
Trials. 2012 Aug 1;13:126. doi: 10.1186/1745-6215-13-126.
Hospitalization may be a particularly important time to promote smoking cessation, especially in the immediate post-discharge period. However, there are few studies to date that shed light on the most effective or cost-effective methods to provide post-discharge cessation treatment, especially among low-income populations and those with a heavy burden of mental illness and substance use disorders.
METHODS/DESIGN: This randomized trial will compare the effectiveness and cost-effectiveness of two approaches to smoking cessation treatment among patients discharged from two urban public hospitals in New York City. During hospitalization, staff will be prompted to ask about smoking and to offer nicotine replacement therapy (NRT) on admission and at discharge. Subjects will be randomized on discharge to one of two arms: one arm will be proactive multi-session telephone counseling with motivational enhancement delivered by study staff, and the other will be a faxed or online referral to the New York State Quitline. The primary outcome is 30-day point-prevalence abstinence from smoking at 6-month follow-up post-discharge. We will also examine cost-effectiveness from a societal and a payer perspective, as well as explore subgroup analyses related to patient location of hospitalization, race/ethnicity, immigrant status, and inpatient diagnosis.
This study will explore issues of implementation feasibility in a post-hospitalization patient population, as well as add information about the effectiveness and cost-effectiveness of different strategies for designing smoking cessation programs for hospitalized patients.
Clinicaltrials.gov ID# NCT01363245.
住院可能是促进戒烟的一个特别重要的时期，尤其是在出院后的即刻时期。然而，迄今为止，很少有研究能够阐明提供出院后戒烟治疗的最有效或最具成本效益的方法，尤其是在低收入人群以及患有严重精神疾病和物质使用障碍的人群中。
方法/设计：这项随机试验将比较两种戒烟治疗方法在纽约市两家城市公立医院出院患者中的效果和成本效益。住院期间，工作人员将被提示询问患者的吸烟情况，并在入院时和出院时提供尼古丁替代疗法（NRT）。患者将在出院时随机分配到两个手臂之一：一个手臂是由研究人员提供的主动多次电话咨询和动机增强，另一个手臂是通过传真或在线转介到纽约州戒烟热线。主要结局是在出院后 6 个月的随访中，30 天点患病率戒烟。我们还将从社会和支付者的角度考察成本效益，并探索与患者住院地点、种族/民族、移民身份和住院诊断相关的亚组分析。
这项研究将探索在出院后患者群体中实施的可行性问题，并提供有关为住院患者设计戒烟计划的不同策略的效果和成本效益的信息。
Clinicaltrials.gov ID# NCT01363245。
