BAY v 3522（一种新型口服头孢菌素）的体外活性

In vitro activity of BAY v 3522, a new cephalosporin for oral administration.

作者信息

Hodges T L, Eliopoulos G M, Klimm K, Moellering R C

机构信息

Department of Medicine, New England Deaconess Hospital, Boston, Massachusetts.

出版信息

Antimicrob Agents Chemother. 1990 Sep;34(9):1849-54. doi: 10.1128/AAC.34.9.1849.

DOI:10.1128/AAC.34.9.1849

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC171947/

Abstract

The activity of BAY v 3522 was tested against over 500 clinical bacterial isolates and compared with the activities of ampicillin, amoxicillin-clavulanate, cefaclor, cefixime, cefuroxime, cephalexin, and/or ciprofloxacin, erythromycin, and metronidazole. BAY v 3522 activity against staphylococci and streptococci equaled or exceeded those of the other agents. BAY v 3522 exhibited no significant advantage over cefaclor, cefuroxime, or cephalexin against gram-negative bacilli.

摘要

对超过500株临床分离细菌测试了BAY v 3522的活性，并与氨苄西林、阿莫西林-克拉维酸、头孢克洛、头孢克肟、头孢呋辛、头孢氨苄和/或环丙沙星、红霉素及甲硝唑的活性进行比较。BAY v 3522对葡萄球菌和链球菌的活性等于或超过其他药物。在针对革兰氏阴性杆菌方面，BAY v 3522相对于头孢克洛、头孢呋辛或头孢氨苄未显示出显著优势。

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