Rybakova M G, Kabakov A B
Arkh Patol. 1990;52(7):26-9.
Opportunistic infection (bacterial, viral, parasitic, fungal) acquires an important role under the conditions of immunodeficiency associated with kidney transplantation. Immunodeficiency results not only from the immunosuppressive therapy, but from the main disease and kidney failure as well. The use of cyclosporin selectively suppressing T-cell immunity makes the infectious complications very similar to those complicating AIDS. Its high toxicity increases feasibility of pulmonary complications.
机会性感染(细菌、病毒、寄生虫、真菌)在与肾移植相关的免疫缺陷条件下起重要作用。免疫缺陷不仅源于免疫抑制治疗,还源于主要疾病和肾衰竭。环孢素的使用选择性抑制T细胞免疫,使得感染并发症与艾滋病相关并发症非常相似。其高毒性增加了肺部并发症的可能性。