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实体器官移植患者的卡氏肺孢子虫肺炎:5例报告

[Pneumocystis carinii pneumonia in patients with a solid organ transplant: a report of 5 cases].

作者信息

Ruiz Ruiz J, Yebra Bango M, Fernández Fernández J, Alonso Pulpón L, Cuervas-Mons Martínez V, Besada Estévez E, Daza Pérez R M

机构信息

Servicio de Medicina Interna I, Clínica Puerta de Hierro, Madrid.

出版信息

Rev Clin Esp. 1997 Jan;197(1):31-4.

PMID:9102669
Abstract

A report is made here of five patients who underwent solid organ transplantation, were not infected with the human immunodeficiency virus, and suffered Pneumocystis carinii pneumonia while receiving immunosuppressive drugs. The figure represents a prevalence of 0.43% among patients with solid organ transplantation at the Clínica Puerta de Hierro. Some features of this infection are reported in patients without AIDS, both transplanted patients and with other clinical conditions, the possible predisposing factors and the necessity to keep a high suspect index when individuals treated with immunosuppressive drugs present with respiratory symptoms. Likewise, a suggestion is made to consider the use of chemoprophylaxis with cotrimoxazole in these cases.

摘要

本文报告了5例接受实体器官移植的患者,这些患者未感染人类免疫缺陷病毒,在接受免疫抑制药物治疗期间罹患卡氏肺孢子虫肺炎。这一数字代表了在耶罗港诊所接受实体器官移植的患者中,该病的患病率为0.43%。本文报道了在无艾滋病的患者中,包括移植患者和患有其他临床疾病的患者,这种感染的一些特征、可能的诱发因素,以及当接受免疫抑制药物治疗的个体出现呼吸道症状时,保持高度怀疑指数的必要性。同样,本文建议在这些病例中考虑使用复方新诺明进行化学预防。

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