Bello-González S A, Bergés-García A
Depto. de Investigaciones Hematológicas, Hospital Infantil de México Federico Gómez, México, D.F.
Bol Med Hosp Infant Mex. 1990 Nov;47(11):737-45.
Peripheral pancytopenia is a syndrome which allows for an early diagnosis, and although is may cover a large number of pathological entities, it can be clearly defined into three groups of illnesses which evolve with this syndromal manifestations. The first group includes non-neoplastic illnesses which include aplastic anemia, hemophagocytic syndrome associated to infection, immunological diseases and the deficiency of folates or vitamin B12. The second group includes neoplastic diseases as acute leukemia, non-Hodgkin lymphoma, and Hodgkin's lymphoma with myelofibrosis, malignant histiocytosis and non-hematological neoplasms, like the neuroblastoma and the embryonal rhabdomyosarcoma. The third group is formed by illnesses which have some similarity with neoplasms.
全血细胞减少是一种可早期诊断的综合征，尽管它可能涵盖大量病理实体，但可明确分为三组疾病，它们都有这种综合征表现。第一组包括非肿瘤性疾病，如再生障碍性贫血、感染相关的噬血细胞综合征、免疫性疾病以及叶酸或维生素B12缺乏症。第二组包括肿瘤性疾病，如急性白血病、非霍奇金淋巴瘤、伴有骨髓纤维化的霍奇金淋巴瘤、恶性组织细胞增多症以及非血液系统肿瘤，如神经母细胞瘤和胚胎性横纹肌肉瘤。第三组由与肿瘤有某些相似之处的疾病组成。
