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一氧化碳中毒致痴呆病例中神经心理学数据与行为治疗反应的关系

Relationship between neuropsychological data and response to behavioral treatment in a case of carbon monoxide toxicity and dementia.

作者信息

Heinrichs R W

机构信息

Department of Psychology, York University, Toronto, Ontario, Canada.

出版信息

Brain Cogn. 1990 Nov;14(2):213-9. doi: 10.1016/0278-2626(90)90030-r.

DOI:10.1016/0278-2626(90)90030-r
PMID:2285514
Abstract

The ability of learning measures to predict a behavioral treatment response was of interest in this study. A severely impaired and behaviorally disturbed female neuropsychiatric patient was unable to demonstrate any learning on "direct" tests involving multiple free recall trials or cued paired associate recall. However, she performed normally on an "indirect" test involving implicit learning of new associations. To assess whether direct or indirect measures tapped the kind of learning required by a positive reinforcement-based treatment approach, a token program was carried out. There was a 72.5% reduction in maladaptive behavior relative to baseline, indicating a positive treatment response. The results are discussed in terms of the potential treatment utility and predictive validity of indirect measures of learning and memory and the relation of neuropsychological data to intervention issues in general.

摘要

本研究关注学习测量方法预测行为治疗反应的能力。一名严重受损且行为紊乱的女性神经精神患者,在涉及多次自由回忆试验或线索配对联想回忆的“直接”测试中无法表现出任何学习能力。然而,她在一项涉及新联想内隐学习的“间接”测试中表现正常。为了评估直接测量或间接测量是否挖掘出了基于正强化的治疗方法所需的那种学习,实施了一个代币计划。与基线相比,适应不良行为减少了72.5%,表明治疗反应良好。本文从学习和记忆间接测量的潜在治疗效用和预测效度,以及神经心理学数据与一般干预问题的关系方面对结果进行了讨论。

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