Ligand-induced MET signaling as targetable codependence in acute myeloid leukemia.
作者信息
Fröhling Stefan
出版信息
Haematologica. 2012 Aug;97(8):1118. doi: 10.3324/haematol.2012.073635.
Abstract
摘要
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本文引用的文献
1
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Nat Med. 2012 Jul;18(7):1118-22. doi: 10.1038/nm.2819.
2
RNAi screening of the kinome with cytarabine in leukemias.用阿糖胞苷进行白血病的激酶组 RNAi 筛选。
Blood. 2012 Mar 22;119(12):2863-72. doi: 10.1182/blood-2011-07-367557. Epub 2012 Jan 20.
3
RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia.RNAi 筛选鉴定 Brd4 为急性髓系白血病的治疗靶点。
Nature. 2011 Aug 3;478(7370):524-8. doi: 10.1038/nature10334.
4
FLT3 ligand impedes the efficacy of FLT3 inhibitors in vitro and in vivo.FLT3 配体在体外和体内会阻碍 FLT3 抑制剂的疗效。
Blood. 2011 Mar 24;117(12):3286-93. doi: 10.1182/blood-2010-01-266742. Epub 2011 Jan 24.
5
RNAi screen for therapeutic target in leukemia.白血病治疗靶点的RNA干扰筛选
Cell Cycle. 2009 Jul 15;8(14):2144.
6
Synthetic lethal interaction between oncogenic KRAS dependency and STK33 suppression in human cancer cells.致癌性KRAS依赖性与人类癌细胞中STK33抑制之间的合成致死相互作用。
Cell. 2009 May 29;137(5):821-34. doi: 10.1016/j.cell.2009.03.017.
7
Principles of cancer therapy: oncogene and non-oncogene addiction.癌症治疗原则：癌基因与非癌基因成瘾
Cell. 2009 Mar 6;136(5):823-37. doi: 10.1016/j.cell.2009.02.024.
8
Deregulation of signaling pathways in acute myeloid leukemia.急性髓系白血病中信号通路的失调
Semin Oncol. 2008 Aug;35(4):336-45. doi: 10.1053/j.seminoncol.2008.04.004.
9
A loss-of-function RNA interference screen for molecular targets in cancer.一项针对癌症分子靶点的功能丧失型RNA干扰筛选。
Nature. 2006 May 4;441(7089):106-10. doi: 10.1038/nature04687. Epub 2006 Mar 29.
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Oncogene. 2004 Nov 1;23(51):8376-83. doi: 10.1038/sj.onc.1208073.
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