Everson Richard B
Cancer Prevention and Control, Carole and Ray Neag Comprehensive Cancer Center, University of Connecticut Health Center, Farmington, USA.
Conn Med. 2012 Jun-Jul;76(6):359-64.
The goals of cancer control are to reduce cancer risk, detect cancers earlier, improve treatments and enhance the health of cancer survivors. Personalized medicine aims to customize health care by tailoring care to the individual patient using genetic and other information. This review considers the traditional strengths of Connecticut's cancer control program as well as trends in emerging science, primarily under development through the auspices of the National Cancer Institute's Division of Cancer Control and Population Sciences. It focuses on resources for cancer control offered by the Connecticut Tumor Registry in addition to opportunities for improving cancer control through developments in informatics and cancer genomics. It provides an overview of the use of informatic tools, electronic health records, health information exchange, integration of genotyping into risk models, and genomic analyses of clinical tumor specimens, demonstrating how the common theme in these advances will lead toward more personalized cancer control.
癌症控制的目标是降低癌症风险、更早地检测癌症、改善治疗方法并提高癌症幸存者的健康水平。精准医学旨在通过利用基因和其他信息为个体患者量身定制医疗保健服务。本综述考虑了康涅狄格州癌症控制项目的传统优势以及新兴科学的发展趋势，这些趋势主要是在美国国立癌症研究所癌症控制与人口科学司的支持下进行的。它重点关注康涅狄格肿瘤登记处提供的癌症控制资源，以及通过信息学和癌症基因组学的发展改善癌症控制的机会。它概述了信息工具的使用、电子健康记录、健康信息交换、将基因分型整合到风险模型中以及临床肿瘤标本的基因组分析，展示了这些进展中的共同主题将如何朝着更精准的癌症控制方向发展。
